Observer-independent quantification of movement disorders using accelerometry

Movement disorder syndromes are defined by increases or reductions of movement, either voluntary or involuntary. They are linked to neurological disorders such as Parkinson’s disease and Huntington’s Chorea.

Historically, the assessment of movement disorders relied on clinical rating scales or patient self-report. These methods are inherently subjective, non-linear, and limited to specific times of observation. Accelerometry provides observer-independent quantification of movement with sensitive output measures suitable for statistical analysis.

How our technology helps

The GENEActiv measures movement directly through the acceleration created by body movement. The high-resolution data can identify and quantify changes in gait, reductions in movement and tremor. The device is well tolerated by patients and can be worn continuously to understand general temporal patterns or compare nocturnal and diurnal symptoms.

These same capabilities can be applied to other conditions where movements patterns are important for research and diagnosis. Scratching and stimming behaviours produce characteristic repetitive patterns of movement that can be categorised and characterised. Reductions in movement can also be detected to inform the assessment of disease progression and strength deterioration in, for example, frailty.